Download Annual Review of Gerontology and Geriatrics, Volume 3, 1982: by Carl Eisdorfer PhD MD PDF

By Carl Eisdorfer PhD MD

Manhattan 1982 Springer. 8vo, 436pp., index, unique gilt published hardcover. VG, tiny chip on entrance, no DJ.

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Extra info for Annual Review of Gerontology and Geriatrics, Volume 3, 1982: Clinical, Behavioral and Social Issues

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J. Gerontol. 29:261. , and Weksler, M. E. 1981. Immunological studies of aging. Decreased production of and response to T-cell growth factor by lymphocytes from aged humans. J. Clin. Invest. 67:937. 24 BIOLOGICAL SCIENCES Goidl, E. , Innes, J. , and Weksler, M. E. 1976. Immunological studies of aging. II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice. J. Exp. Med. 1445:1037. Goidl, E. , Schrater, A. , Siskind, G. , and Thorbecke, G. J. 1979.

Weksler, M. , and Siskind, G. W. 1980. Effect of age on ease of B-cell tolerance induction. Cell. Immunol. 55:66. , and MacSween, J. 1980. Decreased autologous mixed lymphocyte reaction with aging. Mechanisms of Ageing and Development 12:245. , and Cinader, B. 1974. Cellular aspects of tolerance. V. The in vivo cooperative role of accessory and thymus derived cells in responsiveness and unresponsiveness in SJL mice. Cell. Immunol. 12:194. , Smith, G. , and Walford, R. L. 1974. Age related decline in thymic independent immune function in a longlived mouse strain.

Many different mutations affecting G6PD cause enzyme deficiency. The Mediterranean type G6PD deficiency (about 3 to 5 percent of American males of Greek, Italian, or Sardinian ancestry) is more severe than the Negro type (about 15 percent of American black males); thus, a larger number of oxidizing drugs are a threat. Beutler (1978) has published a painstaking analysis of the primary literature and the drug/infection interactions in an effort to determine which drugs are a significant hazard in G6PD-deficient individuals and which can, in fact, be given safely in usual therapeutic doses.

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