By H.-J. Biersack (auth.), Hans Bender MD, Holger Palmedo MD, Hans-Jürgen Biersack MD, Peter E. Valk MD (eds.)
Clinical reports in past times 10 years have proven that puppy is extra delicate than CT and MRI for the detection of many tumors. in lots of instances, in spite of the fact that, for instance in head and neck tumors, mix with radiological systems is important. it can be speculated that puppy will be the 1st examine in a malignant tumor while metastatic unfold is suspected. MRI and CT could then be constrained to these physique parts which evince websites of elevated glucose metabolism. hence, a mix of metabolic and morphologic tactics will increase tumor detection and alter the healing process. during this mild, an atlas together with puppy, CT, MRI, and histology information turns out fascinating to mix metabolic and morphologic imaging. This publication provides an outline of the to be had info which will be of serious curiosity not just for experts in radiology and nuclear drugs, but additionally for oncologists.
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Additional info for Atlas of Clinical PET in Oncology: PET versus CT and MRI
Technique: Transmission-corrected scans with a slice thickness of 4 mm, iterative image reconstruction. PET Results: The coronal (a), transaxial (b) and sagittal (c) views show one of two small foci in the left, middle cervical region. No other lymph node or distant metastases were detected. Histology: Squamous cell carcinoma; pT3 N2 Mo. Figure 7a-c Diagnosis: Oropharynx cancer with lymph node metastases. Patient and History: 65-year-old patient with a tumor suspected mass in the left neck. Technique: Transmission-corrected scans with a slice thickness of 4 mm, image reconstruction by filtered backprojection.
CT also had ten false positive findings in the abdomen and pelvis, compared to three by PET. In the liver, the difference between the modalities was less at 11 %, and resulted mainly from difficulty in differentiating benign from malignant abnormalities by CT. PET was also more specific than CT, but the difference between the two modalities was smaller. Delbeke et al.  compared PET and CT to CT portography, which is more invasive and more expensive than PET or CT alone. For detection of hepatic metastasis, PET was more accurate than CT or CT portography (92 %,78 % and 80 % accuracy respectively).
If PET is to be used in a more limited fashion, the following represent minimum indications for its use: - Preoperative staging of recurrent tumor. - Rising serum CEA level or clinical suspicion of recurrence and negative CT findings. - Equivocal abnormality by CT imaging. 6 Technical Issues Attenuation correction of images is important in colorectal cancer because of artifacts that are seen in non-corrected images of high-activity structures, including the renal collecting systems and the bladder.