Download Chemotherapy for Gynecological Neoplasms: Current Therapy by R Angioli; et al PDF

By R Angioli; et al

Files fresh advances in gynecological oncology, belly and pelvic surgical procedure, and molecular biology during this reference for physicians and surgeons. The e-book starts with fabric on simple ideas of chemotherapy, with emphasis at the mechanisms of motion of assorted medications, and on immunotherapy, gene treatment, and pharmacogenomics. basic scientific elements of chemotherapy are mentioned, akin to supportive Read more...

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Downregulation of HER2-neu may decrease DNA repair and/or enhance apoptotic cell mechanisms (211). HER2-neu downregulation can be achieved via any of the following: 1. Antisense oligonucleotides, 2. Monoclonal antibodies (limited to work at the cell surface and not intracellularly), 3. Inhibition of P184HER2 neu tyrosine kinase activity, 4. , EIA, SU40 large T antigen) (205,213). All of these mechanisms are being investigated for therapeutic interventions. Ras Oncogene Ras gene codes for a G protein located in the plasma membrane that plays a pivotal role in multiple pathways involved with amplification of abnormal signals.

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