By Vera Price, Paradi Mirmirani
Written via prime global specialists, Cicatricial Alopecia: An method of analysis and Management is the 1st booklet at the prognosis and remedy of basic cicatricial (scarring) alopecia.
The ebook presents an in-depth dialogue of the first cicatricial alopecias. preliminary chapters introduce the topic with special and systematic descriptions of scientific evaluate of the sufferer, dermatopathology, clinical administration, and mechanisms and present examine.
The next chapters persist with a traditional instructing structure and start with a medical situation of a sufferer and clues to the prognosis, continue to a common dialogue that's widely illustrated with scientific images, and finish with useful take-away pearls and recommended readings in the event you desire to pursue an issue in better intensity. a last bankruptcy comprises contributions via sufferers that spotlight the disappointment that many of us with cicatricial alopecia event to find a doctor who can safely diagnose and deal with their disorder.
Dermatologists and dermatology citizens and fellows, who're looking for a consummately functional and authoritative quantity at the scarring alopecias, will locate this ebook an quintessential addition to their scientific library.
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Additional resources for Cicatricial Alopecia: An Approach to Diagnosis and Management
Intralesional. Injection of triamcinolone acetonide 10 mg/cc to inflamed, symptomatic sites Culture nostrils. If staph carrier, apply topical mupirocin ointment to nostrils daily for 1 week, then once per month. For dissecting cellulitis. Culture often does not grow a pathogen. Isotretinoin is helpful in some patients. Starting dose must be small: 10–20 mg per day for 6–12 months. For infliximab, adalimumab, etanercept in dissecting cellulitis, see “Dissecting cellulitis” in Chap. 8. For folliculitis keloidalis: for early mild disease: class 1 or class 2 topical corticosteroids with or without topical antibiotics; for papules and nodules: intralesional triamcinolone acetonide (10 mg/ml) every 4–6 weeks, along with topical antibiotics, or oral antibiotics such as tetracycline, doxycycline, minocycline; for advanced disease, excisional surgery may be necessary.
1 Histopathological distinction of LMPCA and NMPCA LMPCA NMPCA Infiltrate: Rich in lymphocytes Sebaceous glands: Compound follicles: Loss affecting most follicles Fusion of two (rarely three) infundibula Limited to the adventitial dermis; concentric in areas of early involvement Uncommon and few Rich in neutrophils and histiocytes early, and rich in plasmacytes late Loss affecting most follicles Fusion of four or more infundibula Fibrosis: Parafollicular granulomas: Involves both the adventitial and reticular dermis jointly Common and sometimes numerous 3 Dermatopathology Lymphocyte-Mediated Primary Cicatricial Alopecias LPP represents the prototypical form of cicatricial alopecia with an associated lymphocyte-rich infiltrate (1–3).
Cephalexin 500 mg 4 times daily for 10 weeks with oral rifampin 600 mg every morning for 10 days. May substitute: clindamycin 300 mg twice daily, or ciprofloxacin 750 mg twice daily, or doxycycline 100 mg twice daily, all given for 10 weeks and with rifampin 600 mg every morning for 10 days; or sulfamethoxazole-trimethoprim DS twice daily for 10 weeks. Topical. Clindamycin phosphate topical solution 1%, or clindamycin phosphate topical gel 1%, dapsone gel 5%, mupirocin ointment or cream, and Derma-Smoothe/FS scalp oil (sometimes 4 Medical Management soothing, sometimes not tolerated), antiseborrheic shampoos.