By B. Pomeranz (auth.), Gabriel Stux M.D., Richard Hammerschlag Ph. D. (eds.)
There is a big bring up in curiosity in acupuncture by way of well-being care shoppers. the 3 major purposes for this are clinical effectiveness, rate effectiveness and the credibility that scientific trials and physiological examine have supplied. Acupuncture is swiftly relocating out of the sector of "alternative" medication, largely back since it is grounded extra firmly than different replacement remedies in examine. The e-book offers the reader with the updated info at the medical bases of acupuncture.
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Additional info for Clinical Acupuncture: Scientific Basis
Guo HF, Tian J et al (1996) Brain substrates activated by electroacupuncture (EA) of different frequencies (II): Role of Fos/Jun proteins in EA-induced transcription of preproenkephalin and preprodynorphin genes. Brain Res. Molecular Brain Res 43:167-173 61. Gunn CC, Milbrandt WE et al (1980) Dry needling of muscle motor points for chronic low-back pain. Spine 5:279-291 62. Ha H, Tan EC, Fukunaga H, Aochi 0 (1981) Naloxone reversal of acupuncture analgesia in the monkey. Exp Neurol 73:298-303 63.
Beta-endorphin and ACTH released concomitantly from the pituitary gland might be the presynaptically acting neurohumoral factors in AA and non-AA, producing dopaminergic transmission in the P-HARN (Fig. 5). The possibility that ACTH acts as a neurohumoral factor in other regions of the non-AA afferent pathway has been examined by recording potentials evoked by nonacupoint stimulation after lesioning in the A-HARN, the final station of the non-AA afferent pathway. Such evoked-potentials in the A-HARN are enhanced by intraperitoneal administration of ACTH and are markedly decreased by hypophysectomy.
Analgesia produced by stimulation of both the HVM and the P-HARN is associated with the second category. Synaptic transmission from the P-HARN to the HVM is apparently dopaminergic, since analgesia produced by stimulation of the P-HARN is blocked by lesions of the HVM or by dopamine antagonists (Fig. 1). Mechanisms of Acupuncture Analgesia Produced by Low Frequency Electrical Stimulation 31 AA afferent pathway NAA afferent pathway Efferent pathway descending pain inhibitory system ! ":~-m~~-1 H~f/ /1 d-raphe ~-- .................